Flow Cytometry

Since 1987, when Dr. Stanley McCormick became the director, this laboratory has emphasized
clinical diagnostic service. At the same time, we have also maintained a research program designed to provide hematopathologists and oncologists with the most current diagnostic testing. Our dual-laser Coulter Elite flow cytometer, in combination with our rigorous attention to technical detail, makes us one of the most advanced laboratories in the Upper Midwest. Flow cytometry is becoming indispensable		Breast cancer sample prepared for flow cytometric analysis. Cells dual stained for DNA (red) and cytokeratin (green).
in diagnosing a wide range of conditions (for example, Paroxysmal Nocturnal Hemoglobinuria (PNH), or Trophoblastic Disease) as well as providing useful prognostic information in malignancies.

Test offerings (Follow the hyperlink to obtain sample requirements, etc.):
DNA Ploidy	This test is used as a diagnostic and prognostic indicator in solid tumors by measurement of nuclear DNA. Non-tumor cells are eliminated by cytokeratin gating.
Leukemia/Lymphoma Panel	This panel is used in the diagnosis and clinical management of acute and chronic hematologic malignancies. The panel is tailored to each case after morphologic review by a pathologist.
TdT by Flow	Terminal deoxynucleotidyl transferase (TdT) by flow cytometry is useful in the diagnosis, and follow up of patients with acute lymphoblastic leukemia, myeloid leukemia, or lymphoblastic lymphoma.
BLAST Enumeration	Flow cytometry for minimal residual disease analysis of leukemic cells previously characterized for lineage-associated markers.